Asymmetric Catalysis & Total Synthesis

Replication and Modification of Nature's Creation

M.Sc. - Advisor: Professor Tabrez Khan

Publication 1: "Total Syntheses of Several Iridolactones and the Putative Structure of Noriridoid Scholarein A: An Intramolecular Pauson–Khand Reaction Based One-Stop Synthetic Solution” - A. Salam, S. Ray, M. A. Zaid, D. Kumar, T. Khan* - Org. Biomol. Chem. 2019, 17, 6831-6842

Ph.D. - Advisor: Professor Santanu Mukherjee

Publication 2: "Enantioselective Total Synthesis of [3]-Ladderanol through Late-Stage Organocatalytic Desymmetrization” - S. Ray, S. Mondal, S. Mukherjee* - Angew. Chem. Int. Ed. 2022, 61, e202201584

Publication 3: "Mechanism and Origin of Remote Stereocontrol in the Organocatalytic Enantioselective Formal C(sp2)–H Alkylation Using Nitroalkanes as Alkylating Agents” - S. C. Mallojjala, R. Sarkar, R. W. Karugu, M. S. Manna, S. Ray, S. Mukherjee*, J. S. Hirschi* - J. Am. Chem. Soc. 2022, 144, 17399-17406

Publication 4: "Catalytic Enantioselective Desymmetrization of Cyclopropane Fused Cyclohexene-1,4-diones by a Formal C(sp2)‒H Alkylation” - S. Ray, S. Mukherjee* - Synlett 2023, 34, 863-867 [Cover Page] [Synlett Best Paper of the Year 2023]

Publication 5: "Centrally Chiral Arenes: From Concept to Catalytic Enantioselective Synthesis” - S. Ray, B. Ghosh, S. Mukherjee* - AsiaChem 2023, 3, 34-41

Publication 6: "Alkoxy-Directed Dienamine Catalysis in [4+2]-Cycloaddition: Enantioselective Synthesis of Benzo-[3]-ladderanol” - S. Ray, D. Behera, M. S. Harariya, S. Das, P. K. Tarafdar, S. Mukherjee* - J. Am. Chem. Soc. 2025, 147, 2523–2536

Publication 7: "Alkylative Desymmetrization as Symmetry-Inspired Unified Strategy for the Enantioselective Synthesis of (–)-[5]-Ladderanoic Acid and Unnatural Inverse-[3]-ladderanols” - S. Ray*, S. Das, D. Behera, P. Biswas, P. K. Tarafdar, S. Mukherjee* - An earlier version of this manuscript has been deposited to ChemRxiv: https://doi.org/10.26434/chemrxiv-2025-gmdmv

Patent

Patent 1: "Benzo Compounds and Process Thereof” - S. Ray, S. Mukherjee - Indian Patent Appl. No.202441088524 [15th Nov 2024]

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Asymmetric Catalysis: Research